Pyometra
Pyometra is a severe bacterial infection with accumulation of pus within the uterus. Though it often occurs in middle-aged or older females that have never had puppies, younger dogs are sometimes affected. The condition most commonly develops a few weeks after a heat period. It results from hormonal influences that decrease the normal resistance to infection. As a result, bacteria enters the uterus when the cervix is open during the heat period. It results from hormonal influences that decrease the normal resistance to infection. As a result, bacteria enter the uterus when the cervix is open during the heat period, and in the infection results. If the cervix closes after infection, large volumes of pus can accumulate. Signs of the pyometra include loss of appetite, excessive thirst, depression and vomiting. Sometimes there is discharge of pus from the vagina. The disease may develop very slowly over several weeks. Surgery consists of removal of both ovaries and the uterus. Because the patient is ill and the uterus is infected, the surgery is more complicated and carries a higher risk that a routine spaying in a healthy animal. Postoperative treatment includes antibiotics and intravenous fluids.